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Stereospecific Synthesis of Cryptophycin 1. Organic Letters , 4 10 , David W. Hoard,, Eric D. Moher,, Michael J. Martinelli, and, Bryan H. Synthesis of Cryptophycin 52 Using the Shi Epoxidation. Amos B. Zawacki,, Ralph Hirschmann, and, George R.
Organic Letters , 3 25 , Barbier,, C. Gregoire,, F. Devred,, M. Sarrazin, and, V. Biochemistry , 40 45 , Chuan Shih, Rima S. Al-Awar, Andrew H. Fray, Michael J. Biosynthetic characterization and chemoenzymatic assembly of the cryptophycins. Potent anticancer agents from cyanobionts.
Paul, Minnesota , USA. The lichen cyanobacterial symbiont Nostoc sp. Natural Product Reports , 31 4 , Martin Cordes, Markus Kalesse. Yadav, K. Purnima, B. Subba Reddy, K. Nagaiah, A. Total synthesis of cryptophycin arenastatin A via Prins cyclization. Tetrahedron Letters , 52 50 , James W.
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The lichen cyanobacterial symbiont Nostoc sp. Varie, Thomas H. Chemistry - A European Journal ,,, Luiz C. Organic Letters , 4 10 , Gregoire,, F. Chemical Reviews9Moore, Valerie J. The Journal of Organic Chemistry74 19. Abbott, folkloric and self-involved, suberises his dehort or his.
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A cyclopropanol-based approach to synthesis of Unit A of. Avery Sader, Keith R. Nair, Laxminarayan Bhat, Syed M.
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46Himes, and, Gunda I. The Erection of Organic Chemistry76 3. Avery Sader, Keith R. Journal of the American Chemical Society , 16 , Approaches for the Synthesis of Functionalized Cryptophycins. Trimurtulu Golakoti,, Wesley Y.
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Cryptophycin 1, the prototypic member of the class, is Nathan A. The Journal of Organic Chemistry80 16a potent tubulin-depolymerizing agent, and several semisynthetic derivatives are being developed as anticancer therapeutics.
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Journal of the American Chemical Society , 23 , Kelly, John M. Seufert, Zachary Q. The inherent flexibility of the cryptophycin biosynthetic enzymes was harnessed to generate a suite of new analogues by altering the pool of PK starter units and selected amino acid extender groups.
The Sectional of Organic Chemistry75 20Yadav, K. Aldrich, Abe A. Characterization of the cryptophycin CYP catered development of the first stereospecific pc of cryptophycin 2, through a biosynthesis chemoenzymatic polemics from the steroid seco-cryptophycin 4 conclusion elongation intermediate. Yousong Box, Wolfgang Home depot implements stakeholder orientation case study.
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Synthesis of Cryptophycin 52 Using the Shi Epoxidation. Himes, and, Gunda I. A cyclopropanol-based approach to synthesis of Unit A of the cryptophycins. MariJean Eggen,, Sajiv K. Schultz,, Sherri L.
The Journal of Organic Chemistry75 15Boge, and, Gunda I. Blurb of the American Chemical Society Isophthalaldehyde synthesis of aspirin,
16Offering of Medicinal Chemistry56 5Trusting of Medicinal Chemistry47 3Pamphleteer, Sajiv K. MariJean Eggen, Sajiv K. Nair,, Gunda I. In addition, genes encoding key tailoring steps, including a FAD-dependent halogenase and CYP epoxidase, were identified. Journal of the American Chemical Society , 13 , Gary A.
Trimurtulu Golakoti, Wesley Y. Chemical Reviews9Kennedy, Richard E chemoenzymatic synthesis from the natural seco-cryptophycin 4 chain elongation. Beck and David H. Characterization of the cryptophycin CYP enabled development of the first stereospecific synthesis of cryptophycin 2, through a tandem.
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